Science: Removing amines from combinatorial libraries.
نویسندگان
چکیده
منابع مشابه
Stochastic Similarity Selections from Large Combinatorial Libraries
A stochastic procedure for similarity searching in large virtual combinatorial libraries is presented. The method avoids explicit enumeration and calculation of descriptors for every virtual compound, yet provides an optimal or nearly optimal similarity selection in a reasonable time frame. It is based on the principle of probability sampling and the recognition that each reagent is represented...
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A unique type of combinatorial protein libraries has been constructed. These libraries are based on the pre-B cell receptor (pre-BCR). The pre-BCR is a protein that is produced during normal development of the antibody repertoire. Unlike that of canonical antibodies, the pre-BCR subunit is a trimer that is composed of an antibody heavy chain paired with two surrogate light chain (SLC) component...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2000
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac002730v